WebHow Grapefruit Juice Affects Some Drugs. When drugs are swallowed, they may be broken down (metabolized) by enzymes and/or absorbed using transporters in cells found in the small intestine. ... Some drugs, like certain statins used to lower cholesterol, are broken down by enzymes. As shown above, grapefruit juice can block the action of … WebGrapefruit or grapefruit juice affects some statins. Do not drink grapefruit juice if you're taking simvastatin. Grapefruit juice increases the level of simvastatin in your blood and …
Grapefruit and statins: Interaction, side effects, and more
WebSep 25, 2024 · Grapefruit juice contains compounds called furanocoumarins that stop CYP3A from doing its job. As a result, more of the drug is absorbed, making it more powerful than it’s meant to be even toxic in some cases. Not all statins are affected equally by grapefruit juice, so grapefruit fans might want to switch to a statin that’s less affected . WebJun 26, 2024 · For example – taking grapefruit juice with statins increases the risk of adverse effect such as muscle pain and rhabdomyolysis. Drug-disease interaction – where a medicine has a harmful effect on the progress of a disease. For example – beta-blockers can assist patients with heart disease, but they may worsen asthma in the same patient. cultural hearth ap human geography definition
Common Grapefruit Juice Drug Interactions - Drugs.com
WebStatins include atorvastatin (Lipitor), fluvastatin (Lescol XL), lovastatin (Altoprev), pitavastatin (Livalo), pravastatin (Pravachol), rosuvastatin (Crestor, Ezallor) and … WebOct 1, 2010 · But we've known for several years that this citrus fruit and its juice can interact adversely with many prescription drugs, including some of the statins that are widely used to lower cholesterol. (There's some evidence that pomelos, a fruit that resembles grapefruit, and Seville oranges, which are used in making marmalades, have a similar … WebFeb 16, 2024 · Consuming grapefruit or grapefruit juice when taking statins comes with a rare but serious risk of rhabdomyolysis. This … cultural health issues