Cryptotanshinone supplement
WebCryptotanshinone is a STAT3 inhibitor with IC50 of 4.6 μM in a cell-free assay, strongly inhibits phosphorylation of STAT3 Tyr705, with a small effect on STAT3 Ser727, but none against STAT1 nor STAT5. Cryptotanshinone … WebNov 5, 2024 · Cryptotanshinone (CT) is an extract from the traditional Chinese medicine Salvia miltiorrhiza, which inhibits the growth of methicillin-resistant Staphylococcus …
Cryptotanshinone supplement
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WebJun 26, 2013 · Cryptotanshinone Inhibits STAT3, but Not STAT5, Signaling in K562 Cells. Parallel assays were carried out in cryptotanshinone-treated K562 cells. ... these … WebJul 13, 2024 · Traditionally, danshen has been used to improve body function (eg, promote circulation, blood flow), as well as to treat hemorrhage, dysmenorrhea, miscarriage, …
WebApr 18, 2024 · Cryptotanshinone (CTs), one of the major tanshinones isolated from the root of SM, is a kind of lipophilic compound and can pass through BBB ( 9, 10 ). CTs has various biological activities, such as anti-oxidation, anti-inflammation, anti-tumor, anti-apoptosis, anti-platelet aggregation activities, and so on ( 11 – 14 ). WebJul 5, 2024 · Cryptotanshinone (CTS), tanshinone I (TSI) and tanshinone IIA (TSA) are the most widely-studied lipophilic ingredients, but low oral bioavailability limits their clinical …
WebTanshinone IIA (150) is the most abundant lipophilic compound in Danshen. Tanshinone I (144), cryptotanshinone (110 ), and 15,16-dihydrotanshinone I ( 51) are also the main constituents of the plant. Thus, the biological studies have prominently focused on these relatively abundant compounds. WebMay 31, 2024 · Dihydrotanshinone, tanshinone I, cryptotanshinone, and tanshinone IIA are major lipid-soluble constituents isolated from Salvia miltiorrhiza Bunge (Danshen). ... Danshen, as a dietary supplement ...
WebOct 5, 2024 · Cryptotanshinone is a major lipophilic compound extracted from the root of Danshen and has been reported to exert various pharmacological effects, however, its anti-cachectic remains unknown. Aim of the study: The present study aims to investigate the anti-cachectic efficacy of cryptotanshinone and elucidate the underlying mechanism.
WebFeb 1, 2024 · Cryptotanshinone (CTS) is a principal active constituent in Salvia miltiorrhiza Bunge (Danshen in Chinese), which is a widely used traditional Chinese medicine. CTS … the piano guys tour reviewWebCryptotanshinone Cryptotanshinone (CTS), extracted from the root of Salvia miltiorrhiza Bunge, has a prominent anticancer action through inhibiting activation of STAT3 (Lu et al., 2024). From: New Look to Phytomedicine, 2024 View all Topics Add to Mendeley Download as PDF About this page Pharmacological Advances in Natural Product Drug Discovery sickness pay irelandWebJan 1, 2009 · Cryptotanshinone was identified as a potent STAT3 inhibitor. Cryptotanshinone rapidly inhibited STAT3 Tyr705 phosphorylation in DU145 prostate cancer cells and the growth of the cells through 96 hours of the treatment. sickness pay for part time workersWeb2.4 Antitumor. Tanshinone IIA, cryptotanshinone and tanshinone I are the main antitumor ingredients of Salvia miltiorrhiza. The antitumor mechanisms of tanshinone IIA are as follows: (1) inhibiting the growth and proliferation of cancer cells, (2) inducing apoptosis, (3) inducing cell cycle arrest, and (4) inhibiting the invasion, migration and ... the piano guys wedding processionalWebNational Center for Biotechnology Information sickness paintingWebMar 10, 2024 · Cryptotanshinone (CTS) is a lipophilic constituent of Salvia miltiorrhiza, with a broad-spectrum anticancer activity. We have observed that CTS enhances the efficacy of gefitinib in human lung cancer H1975 cells, yet little is known about its molecular mechanism. To explore how CTS enhances H1975 cell sensitivity to gefitinib, we figured … sickness pay waiting daysWebOct 18, 2024 · Cryptotanshinone is a quinone diterpene extracted from the traditional Chinese medicine Salvia miltiorrhiza root that shows obvious anticancer activity. The aim … the piano handbook pdf