Cd112 antibody
WebRequest Bulk Quote. Description. CD112, known as poliovirus receptor related 2 protein (PRR2), Nectin-2, or Hve B, is a type I transmembrane glycoprotein, a member of the Ig … WebThe R2.525 monoclonal antibody specifically binds to CD112. CD112 is a type I transmembrane glycoprotein that is encoded by NECTIN2 (Nectin cell adhesion molecule 2) which belongs to the Ig gene superfamily. CD112 is also known as polio virus related receptor 2 (PRR2), poliovirus receptor-like 2 (PVRL2) or herpesvirus entry protein B (HveB).
Cd112 antibody
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WebOct 28, 2014 · Blots were probed with antibodies specific for CD112, CD155, and gD as well as for gB and gC (infection controls) and tubulin (loading control). As shown in Fig. S1 A , WT PRV-infected cells showed substantially reduced CD112 protein levels compared with mock-infected cells or cells infected with gDnull PRV, whereas CD155 protein levels … WebAbout This Program. This program aims to develop anti-CD112 therapeutic monoclonal antibody for immuno-oncology. CD112 acts as an organizer for Sertoli and sperm cell …
WebCD112, known as poliovirus receptor related 2 protein (PRR2), Nectin-2, or Hve B, is a type I transmembrane glycoprotein, a member of the Ig gene superfamily. It is primarily found on myelomonocytic cells, megakaryocytes, dendritic cells, mast cells, CD34 positive stem cells, endothelial cells, epit WebBackground: Nectin-2/CD112 Nectins are a small family of Ca ++-independent immunoglobulin (Ig)-like cell adhesion molecules (CAMs) that control cell adhesion, proliferation, and migration (1, 2, 3).The name Nectin derives from the Latin word necto, which means “to connect”.The Nectin family contains four members (Nectin-1 to -4), all …
WebThere are no reviews for Nectin-2/CD112 Antibody (FAB2229B). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount. Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen; Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen; Submit a Review. Product General Protocols ... WebCD112 (Nectin-2) can serve as a ligand for CD226 (DNAM-1) that is involved in NK and T cell-mediated cytotoxicity against certain target cells including certain tumors. The CD112 (Nectin-2) protein also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and thus is involved in cell-to-cell spreading of ...
WebJan 15, 2024 · An antibody-based blockade of CD112 also significantly reduced T cell transmigration across endothelial monolayers in vitro. Moreover, T cell homing to the spleen was significantly reduced in CD112-deficient mice. Overall, our results identify CD112 as a regulator of angiogenic processes in vivo and demonstrate a novel role for CD112 in T …
WebJan 8, 2024 · For example, CD226 competes with TIGIT and CD96 for binding to CD155 (Nectin-like molecule 5, Necl-5, PVR) and CD112 (Nectin-2), and the expression of … imperialism and the developing worldWebCells were incubated with an excess of purified unconjugated CD112 (REA1195) antibody followed by staining with fluorochrome-conjugated antibodies of other known clones against the same marker. Based on the fluorescence signal obtained, the clones were identified as recognizing completely overlapping (++), partially overlapping (+), or ... imperialism and the great warWebThere are no reviews for Nectin-2/CD112 Antibody (NBP1-31486). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount. Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen litchfield pipeWebMonoclonal antibody is produced by immunizing animals with recombinant protein specific to the amino terminus of human Nectin-2/CD112 protein. Background Nectin-2, also known as CD112 and poliovirus receptor … imperialism as a foreign policyWebDetects human Nectin‑2/CD112 in direct ELISAs and Western blots. In direct ELISAs and Western blots, less than 2% cross-reactivity with recombinant human (rh) Nectin-1, rhNectin-3 and rhNectin-4 is observed. Test in a species/application not listed above to receive a full credit towards a future purchase. imperialism dbq answer keyWebApr 9, 2024 · Products > MaxPab® Antibody > Human > Binding > Others - Product List - Abnova. Innovate through Integrated Solutions Home; Contact Us; English ... imperialism belgium and africaWebDisclosed herein are novel compositions and methods for stimulation of and the production or expansion of natural killer (NK) cells. Numbers of NK cells can be increased following contact with exosomes modified with one or more stimulatory peptides. Methods and compositions for the production of exosomes, wherein the exosomes comprises … imperialism cause ww2 because